A Dispensing Booth (Negative Pressure Weighing Room) is a controlled environment designed for handling powders and fine particulate materials. It utilizes vertical laminar airflow and negative pressure to ensure operator safety, prevent dust escape, and protect the surrounding environment, fully complying with GMP standards.
Airflow Design and Multi-Stage Filtration
The negative pressure weighing room features a multi-stage filtration system for optimal air cleanliness:
Primary (Pre-) Filter: Recirculated air first passes through a primary filter to remove large dust particles and protect downstream filters.
Medium-Efficiency Filter: The pre-filtered air is then processed through a medium filter for secondary filtration, extending the service life of the HEPA filter.
HEPA Filter: Under the pressure generated by a centrifugal fan, air passes through the HEPA filter to achieve cleanroom-level standards.
Clean air is delivered to the supply plenum, with 90% flowing through an airflow distribution panel to form uniform vertical laminar flow over the work area, while 10% is directed through an adjustable exhaust damper. All supply and exhaust air is HEPA-filtered, ensuring no residual dust and preventing secondary contamination.
Dust Control and Negative Pressure
Within the work zone, stable vertical laminar flow carries dust generated during dispensing toward the primary and medium-efficiency filters for capture. The system also includes 10% exhaust airflow, creating negative pressure relative to the external environment to prevent dust from escaping and protect surrounding areas.
Applications
Dispensing Booths (Negative Pressure Weighing Rooms) are widely used in:
Pharmaceutical powder handling
Biotechnology laboratories
Fine chemical operations
Any environment requiring GMP-compliant, contamination-free operations
Conclusion
A Dispensing Booth (Negative Pressure Weighing Room) with negative pressure and vertical laminar flow provides effective dust control, operator safety, and GMP compliance. Its multi-stage filtration and precise airflow management ensure a clean working environment, protect personnel, and maintain product quality, making it an essential piece of equipment in pharmaceutical and high-standard laboratory settings.
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